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Another consideration is that the trace gas absorption is regarded as weak ( CL 1) so that the pump depletion along the waveguide can be safely ignored

10.1197/jamia.M2808 38 PaulyA.WolfC.BusseM.StrauA.-C.KrebsS.DrjeF.et al (2015)

Studies differed in extract composition, dosing rationale, species selection, and outcome measures, and several lacked safeguards such as randomisation, blinding, or sample size justification, falling short of ARRIVE 2.0 reporting standards [37]

The term nootropic, coined by Romanian psychologist Corneliu Giurgea, originally described compounds that enhance learning and memory while being virtually non-toxic and lacking the pharmacological effects of typical psychotropic drugs