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Yeilda, Citrate-coated Silver Nanoparticles Loaded with Agomelatine Provide Neuronal Therapy in Acute Cerebral Ischemia/Reperfusion of Rats by Inhibiting the Oxidative Stress, Endoplasmic Reticulum Stress, and P2X7 Receptor-mediated Inflammasome, Environ Toxicol, 39 (2024) 15311543, J.L

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doi: 10.1016/j.jconrel.2020.01.001 202 FukaiTUshio-FukaiMKaplanJH

Several animal studies indicate that MPs reduce gut microbial diversity and shift the dominant phylum ratioparticularly elevating the Firmicutes-to-Bacteroidetes (F/B) ratiowhile depleting beneficial genera like Bifidobacterium and enriching opportunistic pathogens like Staphylococcus 31,36,77

McAndrews, KM, Paradiso, F, Stalnecker, CA, Chellakkan Selvanesan, B, Thege, F, Peng, D, Moreno Diaz, BA, Sugimoto, H, Patel, SI, Mahadevan, KK, Kirtley, ML, Wills, D, Sockwell, AM, Fonseca, AF, Liu, Y, Rajapakshe, K, Yee, N, Tran, PT, Omar, HA, Tedeschi, A, Schischlik-Siegl, F, Boghossian, AS, Rees, MG, Ronan, MM, Roth, JA, Rudolph, D, Aichinger, M, Ebner, F, Artemov, AV, Lipp, J, Pisarsky, L, Herrmann, VL, Park, JE, Rippmann, JF, Schaaf, O, Chandler, V, Williams, M, Deckard, CE, Wang, L , Der, CJ, Vellano, CP, Guerrero, PA, Heffernan, TP, Kalluri, R, Maitra, A