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Figure 1 2 Providing increasing doses of LT4 therapy The optimal treatment for hypothyroidism remains a subject of debate, with the etiology and severity of hypothyroidism and the amount of residual functional thyroid tissue affecting the LT4 dosage (5, DIO2 geneparticularly the common Thr92Ala varianthave been associated with altered enzymatic function and reduced intracellular T3 availability in key tissues, despite normal serum TSH and FT4 levels ( PDE8B ) gene, which encodes a high-affinity cAMP-specific phosphodiesterase, as genetic modulators of TSH levels (34), which evaluated whether targeting TSH in the lower part of the reference range would alleviate persistent symptoms and enhance QoL in patients with primary hypothyroidism

Role of hydrogen sulfide in cognitive deficits: evidences and mechanisms

The Kinetics and mechanism of the reaction of tricoordinate phosphorus compounds with diaryl trisulfides

Food Research International , 52 (1), 144152

Igali S & Gazso L (1980) Mutagenic effects of alcohol and acetaldehyde on Escherichia coli