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FDA reviewers found no human clinical trials at all supporting the proposed uses

This tripeptide, known as glycyl-L-histidyl-L-lysine copper complex, plays a significant role in collagen remodeling and skin repair processes

They are not licensed medicines and are not for human or veterinary consumption

Can occur with Prolia: serious infections, such as UTIs and skin infections skin side effects, such rash or blisters multiple fractures in your spine after stopping Prolia decreased bone production (when it takes longer for your bones to make new bone tissue) Can occur with Reclast: kidney problems, such as decreased kidney function Can occur with both Prolia and Reclast: dental and jaw-related side effects atypical femur fractures (unusual fractures in your thigh bone) severe allergic reaction severe pain in your joints, bones, or muscles Effectiveness Prolia and Reclast have different approved uses, but theyre both used to treat osteoporosis in males* and in females* whove gone through menopause

doi:10.1186/s40200-016-0250-x