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Brinholi FF, Vasupanrajit A, Semeo LO, Michelin AP, Matsumoto AK, Almulla AF, et al

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Epidemiologic studies suggest that repeated mood episodes and even minor, residual symptoms enhance the risk of future recurrences ( Unfortunately, our current diagnostic schema for bipolar disorder, which is based on descriptive nomenclature rather than clearly delineated causal mechanisms, has not given rise to treatments that provide sustained, symptomatic, and functional recovery for many patients ( Is there a way out of this vicious cycle