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References Campbell, J

The central challenge lies in precisely determining whether to inhibit or activate autophagic pathways, a decision that depends on the specific molecular context, including the driver mutation and the resistance mechanism at play

For this reason, we chose two alternative approaches for quantifying assay performance in the presence of epigenetic heterogeneity

Treatment also reduced the number and size of polyps in an Apc -driven transgenic mouse model of intestinal cancer, but again, only in tumors expressing mutant Kras