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At normal concentrations, selenium has a protective effect against several disease states however this protection is lost at lower concentrations and selenium can be toxic at high concentrations

Ten millimolar of glutamylcontaining dipeptide (gluala, glucys, glumet, gluhis or glulys) or glutathione was incubated with 2.5 g of YER163c or ChaC1 protein for 60 min at 37 C in 50 l of reaction mixture containing 50 mM TrisHCl (pH 8)

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Proc Natl Acad Sci U S A 116:1577415783