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doi: 10.1371/journal.pone.0205821 10

CancerProteome: a resource to functionally decipher the proteome landscape in cancer

Bowden, J., Davey Smith, G., Haycock, P

DNA damage causes genomic instability, replication error, induction of signal transduction pathways, induction of transcription and cell cycle arrest, all of which are related to colon carcinoma

Moreover, cytosolic GSTs, which are typically 200-250 amino acids in length, form homo- or hetero-dimers, whereas microsomal GSTs are smaller (nearly 150 amino acids) and form trimers [62, 66]