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Recent research supports that internalized mitochondria can trigger mitophagy through the PINK1-Parkin signaling pathway, a process that clears damaged mitochondria, promotes mitochondrial biogenesis, and restores ATP production

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2011;127(5):e1322-e1325

They reduce mitochondrial oxidative damage by restricting mitochondrial ROS generation and increasing mitochondrial antioxidant systems such as mitochondrial SOD

The following subsections examine well-documented toxins, including benzene, aflatoxins, arsenic, phthalates, airborne PM2.5, and microplastics, and explore their modes of action in relation to cancer risk and progression