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Mitochondria are integral to our survival due to the variety of roles they play in our biochemistry, the most important of which is the production of adenosine triphosphate (ATP) by aerobic respiration [1]

Sarris AH, Viviani S, Bonfante V, Kliche KO, Notti P, Peethambaram P, Tucker S, Preti A, Mesina O, Hagemeister F, Romaguera J, McLaughlin P, Rodriguez MA, Andreeff M , Witzig T, Bonadonna G, Cabanillas F

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The BTB and IVR domains are required for the redox- and electrophile-sensitive regulation of Nrf2 through a series of reactive cysteines [113-115]