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Neuropharmacological review of the nootropic herb Bacopa monnieri

Nitric oxide plays a primary role in regulating the delivery of oxygen to the muscles by relaxing and opening the blood vessels, also known as vasodilation

J.MayatepekE.et al (2014)

Endothelial dysfunction, recognized as a critical feature of vascular aging, is marked by a reduction in NO bioavailability, an elevation in oxidative stress, and a diminished responsiveness to vasodilatory stimuli (18, 19)