how does giving l carnitine work in primary carnitine deficiency Deficiency: What Is It, Causes, Symptoms, and More Carnitine Deficiency - an overview

However, in PD, there is a ROS imbalance in the brain, and excessive ROS induces oxygen stress, damaging various biomolecules such as DNA, proteins, and lipids and eventually causing neuronal cell death [198, 199]

The mechanism involves multiple pathways, but one of the most important appears to be the activation of sirtuins, particularly SIRT1 [5]

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Therapeutic approaches in the improvement of cognitive performance in Down syndrome: Past, present, and future