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Women with high cytoplasmic levels of IGF-1R in epithelial cells found in benign terminal duct lobular units (TDLUs) biopsies, have up to 15 times increased BrCa incidence [72]

doi: 10.3390/cancers13112749

Chromatin immunoprecipitation (ChIP-qPCR) ChIP was performed as previously described (Torres-Garcia et al, 2020b)

FXR agonism and antagonism have both proven to be beneficial in the mitigation of NASH, leading to much controversy in the field, particularly regarding FXR signaling in the gut