glutathione synthetase deficiency red blood cells

glutathione synthetase deficiency red blood cells The Redox Process in Cells: Balancing Oxidants and Antioxidants Frontiers | Glutathione: A Samsonian

Name: glutathione synthetase deficiency red blood cells The Redox Process in Cells: Balancing Oxidants and Antioxidants Frontiers | Glutathione: A Samsonian
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Frontiers Glutathione: A Samsonian life sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation Glutathione reductase Wikipedia Frontiers Case report: A Chinese patient with glutathione synthetase deficiency and a novel glutathione synthase mutation Frontiers Molecular profiles of red blood cells across geographic, pathological, and age related perspectives: translational insights Oxidative Stress Early After Hematopoietic Stem Cell Transplant Transplantation and Cellular Therapy, Official Publication of the American Society for Transplantation and Cellular Therapy

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doi: 10.1083/jcb.200408161 47

These alterations in the composition or quantity of the NFB dimer have been found to alter downstream target gene expression, contributing, in some cells, to increased expression of pro-inflammatory genes and a pro-apoptotic environment (170, 197, 275)

Pharmacological modulators targeting the specific molecular pathways that regulate endosome-initiated inflammation would be beneficial for treating multiple human diseases, including autoimmune and autoinflammatory diseases