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Damage to Cytoskeleton in Cancer Cells The cell cytoskeleton is a fine network structure that can not only maintain cell morphology and maintain the order of cell internal structure but also participate in important life activities such as cell movement, material transportation, information transmission, cell division, and gene expression

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A recent randomized, double-blind, placebo-controlled trial of low dose MTX in patients without known systemic rheumatic diseases showed that low dose MTX was associated with small to moderate risks of adverse events over a median follow-up of 23 months