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Thorarensen, A

Tonetti et al., 1990)

Image: Initial stage of skin changes within the red ink tattoo Copyright: Mateuszczyk MK, yko M, Bieniek A, et al The patients journey: from self-expression to medical crisis In late 2020, a 36-year-old man got a tattoo on his right forearm

However, more severe oxidative stress can cause cell death, and even moderate oxidation can trigger apoptosis, while more intense stresses may cause necrosis

In an IBD context, one could speculate that during epithelial damage, sialylated glycoepitopes (especially those containing Neu5Ac) are exposed or shed, and eosinophils encountering these in the lamina propria via Siglec-8 may be signaled to undergo apoptosis