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Isorhapontigenin ameliorates high glucose-induced podocyte and vascular endothelial cell injuries via mitigating oxidative stress and autophagy through the AMPK/Nrf2 pathway

RNA integrity was detected by agarose gel electrophoresis, and the RNA integrity number (RIN) was determined by an Agilent 2100 Bioanalyzer using the RNA 6000 series II Nano LabChip analysis kit (Agilent Technologies, USA) according to manufacturers recommendations

Enzymes of the CYP3A family are most important in hepatic drug metabolism because of their wide substrate specificity

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