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doi:10.1186/s12970-018-0264-5

3.2.3.3 Immunometabolic regulation of cytokine networks The cytokine profile in the TME precisely regulates the interaction between ferroptosis and ICD by shaping the pro-inflammatory/anti-inflammatory balance

101 As a selective autophagy receptor, p62/SQSTM1, when upregulated in nematodes and Drosophila , can promote protein homeostasis and extend lifespan

This novel finding provides new perspectives regarding the link between Cu-induced cell death and mitochondrial metabolism, advancing our understanding of Cu biology, and shedding new light on cell death pathways