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at least 612 months of intervention, to capture meaningful clinical outcomes rather than short-term surrogate changes), and meaningful primary endpoints (such as improvement in exercise capacity or cardiac function, reduction in hospitalizations or major cardiovascular events, or other hard outcomes like all-cause mortality)

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Water, Centella Asiatica Extract (12.3%), Glycerin, Cetyl Ethylhexanoate, Cetearyl Alcohol, Glyceryl Stearate, Glutathione (1,000ppm), Niacinamide (1,000ppm), Madecassic Acid, Asiaticoside, Asiatic Acid, Solanum Melongena (Eggplant) Fruit Extract, Melaleuca Alternifolia (Tea Tree) Leaf Extract, Hydrolyzed Collagen, Beta-Glucan, Hippophae Rhamnoides Fruit Extract, Nelumbo Nucifera Extract, Artemisia Annua Extract, Oryza Sativa (Rice) Extract, Saccharomyces Ferment, Squalane, Sodium Hyaluronate, Dipropylene Glycol, Butylene Glycol, Hydrogenated Lecithin, Cholesterol, Xanthan Gum, Potassium Hydroxide, Disodium EDTA, Caprylic/Capric Triglyceride, Cyclopentasiloxane, Cyclohexasiloxane, Saccharide Hydrolysate, Sorbitan Stearate, Dimethicone, PEG-100 Stearate, Stearic Acid, 1,2-Hexanediol, Chlorphenesin, Carbomer, Caprylyl Glycol

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Inhaled nitric oxide in premature infants: effect on tracheal aspirate and plasma nitric oxide metabolites