glutathione switch persister cells Ferroptosis Dependence in Drug-Tolerant Cells👇 ✓Chemotherapy or BH3 mimetics trigger mitochondrial outer membrane permeabilization (miMOMP) in a subset of cancer cells. Instead of undergoing full apoptosis, these survive the initial Frontiers | Drug-tolerant persister cells
Frontiers Drug tolerant persister cells in acute myeloid leukemia: pressing challenge and promising new strategies for treatment Cellular Compartmentalization, Glutathione Transport and Its Relevance in Some Pathologies Real Time Monitoring of Glutathione in Living Cells Reveals that High Glutathione Levels Are Required to Maintain Stem Cell Function ScienceDirect Frontiers Drug tolerant persister cells: the deadly survivors in hematological malignancies Targeting of vulnerabilities of drug tolerant persisters identified through functional genetics delays tumor relapse: Cell Reports Medicine
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