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Moreover, it proved more effective and to have fewer adverse gastrointestinal side effects than existing drugs that just targeted GLP-1 (Finan, Ma, Ottaway)

Jagetia and Aggarwal, 2007)

Collectively, these findings demonstrate that necroptotic SMC death and resulting leukocyte activation play a causative role in AAA development and suggest that pharmacological inhibition of MLKL may represent a promising treatment strategy for AAA disease