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After exogenous lactate intervention, primary VSMCs lost their contractile phenotype and differentiated into osteoblasts, accompanied by the increased opening rate of mitochondrial permeability transition pore, a significant decrease in MMP and mitochondrial energy generation capacity, and impaired mitochondrial biogenesis

To date there is no complete understanding of the triggering pathomechanisms of disease, and no quantitative biomarker available with sufficient sensitivity, specificity, and adoptability to provide conclusive diagnosis

Abstract Donkey milk has received increasing attention in recent years due to its unique nutritional composition and potential biological activities

Nuclear factor kappa B: a pro-inflammatory, transcription factor-mediated signalling pathway in lung carcinogenesis and its inhibition by nonsteroidal anti-inflammatory drugs

10.1016/j.bbrc.2005.10.031 125