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The combination of the mTORC1 inhibitor Everolimus to block the mTORC1 signaling pathway and reduce the uptake of glutamine by tumor cells from the extracellular environment may be the key to solving this problem

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All procedures were approved by the ethical committee of the University of Catania (OPBA) and by the Italian Ministry of Health (authorization no

For the 12 week studies the mice were monitored weekly to observe their activity