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Key transcription factors, including TFEB, FOXO proteins, p53, and nuclear factor kappa-light-chain-enhancer of activated B (NF-B), regulate autophagy-related and lysosomal genes

Metabolomic findings were confirmed by reanalysis of a subset of specimens using a targeted MS/MS assay that provided absolute quantification and lower limits of detection (Fig

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Inhibition of ATG7 elevates MHC-I expression, stimulates immunological responses, and reduces cholesterol buildup

Therefore, the search for simple and reproducible methods is still open, with the purpose of obtaining more complete knowledge of the pathophysiological picture of illnesses and determining biomarkers that help with the prognosis and therapeutic monitoring