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Collectively, confinement is a pathophysiologically relevant cue that can influence tumor progression significantly by altering the modes and mechanisms of cancer cell migration, promoting genomic instability, and inducing gene expression changes, which trigger EMT and provide resistance to therapeutic agents

It helps signal tissue repair, improve blood flow, and support the processes your body relies on to rebuild and recover

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As per the latest diagnostic criteria, MetS necessitates the presence of any three out of the following five conditions: elevated fasting glucose or type 2 diabetes (T2D), hypertriglyceridemia, lowered high-density lipoprotein (HDL) cholesterol levels, central obesity, or hypertension (Alberti et al., 2009)

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