endogenous glutathione adducts Stimulation of de novo synthesis by nitrofurantoin for enhanced resilience of hepatocytes | Cell Biology and Toxicology PDF) Endogenous Glutathione Adducts

Phytomedicine 133, 155586

I don't want to run out

34 In August 2013, the FDA alerted consumers of rare but serious and potentially fatal skin reactions, such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP), linked to acetaminophen use

Key Properties Molecular formula: CHNOS Molecular weight: 307.32 Da CAS number: 70-18-8 Appearance: White to off-white lyophilized powder Solubility: Highly soluble in water (~200 mg/mL) Redox pair: GSH GSSG Standard redox potential: ~-240 mV at pH 7 The cysteine thiol group mediates antioxidant and detoxification activity, allowing glutathione to function as a reducing agent and nucleophile

doi: 10.1016/j.freeradbiomed.2006.02.013