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10.3390/jcm10194422 53

Clinical evaluation and investigation of neuropathy

For studies that did not provide SD data, only mean values are included

The proposed mechanism for anti-inflammatory properties of betalains seems to be via interference with NF-kB, which reduces inflammatory mediators, as well as phagocyte cells [137]

The NLRP3 inflammasome, a key inflammatory platform in macrophages, is activated by uremic toxins such as IS, leading to IL-1 maturation and enhanced calcification (58)