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For histopathological examination, 5-m-thick sections were cut and then stained using hematoxylin and eosin [43] before their examination under a light microscope

The other class of alteration represents mutations in ubiquitin ligases which negatively affect their activities

1.5-2mg : Noticeable appetite reduction, early fat loss visible on the scale

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Geriatric For elderly patients, appropriate dose reduction and strict monitoring is required during therapy 4.7 Effects on ability to drive and use machines No studies on the effects on the ability to drive and use machines have been performed