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Metabolic rewiring in the promotion of cancer metastasis: mechanisms and therapeutic implications

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Moreover, although PET-based fluorescence switching enables effective off-on activation, the extent of initial quenching and the magnitude of signal recovery upon activation are highly dependent on the COFs electronic structure and local microenvironment, necessitating precise molecular engineering to balance diagnostic signal-to-noise ratio with therapeutic output

To further substantiate that inhibiting GJs is an effective means of protecting against APAP-induced hepatotoxicity, we utilized the GJ functional inhibitor 2-aminoethoxydipenyl borate (2APB) (Leytus et al