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For example, S1PR1 can utilize Rho kinase and PI3K-Akt1 signaling to modulate peritoneal macrophage migration, whereas S1PR2 can stimulate cAMP production by activating NLRP3 inflammasomes but inhibiting AKT phosphorylation, and thus inhibit macrophage migration [141]

Cell 167 , 260274.e22 (2016)

More recently, H3T11 Histone H3 threonine 11 can be phosphorylated (H3T11ph) by different protein kinases and plays a role in several cellular functions, including meiosis (Shimada et al., 2008), and nutritional stress (Oh et al., 2018)

It is speculated that the interactions between LPAAT and other acyltransferases may disrupt the distribution of acyl groups on glycerol backbone (Chen et al