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These findings are in line with previous studies, further confirming the association between CKD and retinal lesions, while uncovering the potential mechanisms of ferroptosis in retinal degeneration, offering new insights to the existing literature and expanding the pathological research on retinal lesions

The pharmacological action of disulfiram (DSF) is attributed to the inhibition of acetaldehyde metabolism by aldehyde dehydrogenase (ALDH) in the liver 2,3

For instance, IGF-I attenuated the response of theMCF-7 BC cell line to doxorubicin and paclitaxel by at least two mechanisms: induction of proliferation and inhibition of apoptosis (Zeng et al., 2009)

Vitamin D acts as a prohormone

Quantitative analysis confirmed that the inhibitory effect of aloe emodin is better than that of emodin, suggesting distinct mechanisms for each compound against breast cancer metastasis [503]