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( B ) Flow cytometry of CHH stained APEX2 expressing HeLa cells treated with substrate (HPI, 1 mM), H 2 O 2 (100 M, repeated hourly for 5 h) or with the combination of substrate and H 2 O 2

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(2024) 102:aos.15821

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21 Possible role of the GPX4 gene in the development of CS A possible role of glutathione peroxidase-4 in the development of CS has been summarized in Figure 1