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The complexity of these challenges underscores the urgent need for cutting-edge drug delivery technologies like liposomal delivery systems and nanoemulsion drug delivery systems

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1, its antitumor efficacy is driven by pleiotropic actions at both molecular and cellular levels: downregulating pro-survival factors (e.g., Bcl-2, Bcl-xL), inhibiting proliferation pathways (e.g., NF-B, PI3K/Akt/mTOR, STAT3), inducing cell cycle arrest, and promoting programmed cell death [35, 36]

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IGF1, insulin-like growth factor 1 receptor

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