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Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1

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Notably, abiotic and biotic stressors directly shape the cargo of PDEVs, and this influence is particularly evident in the vacuolar pathway: first, small vacuoles (SVs) derived from MVBs can fuse with the central vacuolea connection that links the vacuolar pathway to MVB dynamics [62, 63]