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228 demonstrated that 5-AZa-2-deoxycytidine reversed the changes of the myocardial proteome in rats by inhibiting DNA methyltransferase, reduced myocardial hypertrophy, improved myocardial contractility, and eliminated the susceptibility to ischemic injury

doi:10.3892/etm.2020.9557 Hauser RA, Lyons KE, McClain T, Carter S, Perlmutter D

state Rep

Basic pharmacokinetic parameters including absorption, distribution, metabolism, and excretion characteristics in human subjects would inform rational dosing strategies and identify potential sources of pharmacokinetic variability affecting individual response

The treatment may cause minor bruising which usually improves within a week, but often, recovery is immediate