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Early-life stress (ELS) is a major contributor to neurodevelopmental vulnerability, particularly within the dentate gyrus (DG), where oxidative burden and microglial activation disrupt adult neurogenesis

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doi: 10.1093/cid/cis021 330 AndesDRSafdarNBaddleyJWAlexanderBBrumbleLFreifeldAet al

5 GM-mediated redox homeostasis: direct effects on T-cells The dynamic interplay between the gut microbiome and redox equilibrium within the GI tract constitutes a multifaceted regulatory system influencing host immune responses