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The high-fat diet (HFD) was lard-based and obtained from Ssniff (Germany)

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In contrast, intestinal tumor organoids harboring KRAS mutations are less dependent on extracellular L-serine, compensating instead by upregulating the SSP 125

Additionally, the administration of A1AT reduced airspace size (mean linear intercept [Lm]) by 63% compared with smoke-exposed not treated ( Furthermore, the study demonstrated that A1AT therapy suppressed the increase of TNF-alpha smoke-mediated in serum