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Systemic impacts of metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) on heart, muscle, and kidney related diseases

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Basic and propensity score (PS) matching were performed to limit confounding factors

Clinical research involving approximately 900 participants across six human trials specifically measured serum IGF-1 concentrations and found no changes with AOD-9604 treatment at doses up to 1 mg per day and beyond

Data extraction and synthesis were performed iteratively, with emphasis on clinical relevance and perioperative applicability