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476 The study results suggest that semaglutide may be a more suitable choice for patients with severe insulin deficiency, while dapagliflozin might be effective for a broader range of patients with metabolic abnormalities

Zu den betroffenen spezifischen Signalwegen gehren die TGF-Beta-Superfamilie-Signalwege, Wnt-Signalwege, antioxidative Abwehr (einschlielich Superoxiddismutase, Glutathion-S-Transferasen und Thioredoxinreduktase) sowie DNA-Reparaturmechanismen