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24 CaoH.ZuoC.HuangY.ZhuL.ZhaoJ.YangY.et al (2021)

doi: 10.1055/s-0029-1220752 9 Uehara-WatanabeNOkuno-OzekiNMinamidaANakamuraINakataTNakaiKet al

Reactive oxygen species-mediated c-Jun NH(2)-terminal kinase activation contributes to Hepatitis B virus X protein-induced autophagy via regulation of the beclin-1/Bcl-2 interaction

Preclinical studies demonstrated that AOD-9604 was generally safe after chronic oral application in rats and cynomolgus monkeys, with no genotoxic concerns identified