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While youre not likely to run into MPTP (unless youre taking synthetic street drugs), it is chemically similar to a commonly used herbicide called paraquat.[ref] Subsequently, a number of studies have shown that higher paraquat exposure increases the risk of Parkinsons disease.[ref] Monoamine Oxidase increases ROS: When monoamine oxidase breaks down a monoamine (neurotransmitters, tyramine, etc.), the reaction produces hydrogen peroxide and possibly ammonia, which are reactive oxygen species (ROS)

Xu H, Yang HJ, Rose GM, Li XM

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doi: 10.1113/jphysiol.2010.197392

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