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GSH is capable of scavenging ROS through Nrf2-mediated heme oxygenase-1 induction and enhancing M1-like macrophage polarization regulation, showing that GSH may be a useful strategy to increase the human defense system (Mittal et al., 2014

Vitamin B12 is also required for the healthy operation of the digestive system

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et al., 2011) and a study that included 50 cases of male ALS patients concluded that in men with baseline serum -tocopherol below the average, there was a non-significant decrease in ALS risk in those receiving -tocopherol supplementation (50 mg/day) compared to those not receiving -tocopherol

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4 + T cell subsets