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The metabolism and excretion of acrolein, as well as of its metabolites from the respiratory system, should be given high priority as there is an almost total lack of information about these processes

Hypoxia induces tumor aggressiveness and the expansion of CD133-positive cells in a hypoxia-inducible factor-1alpha-dependent manner in pancreatic cancer cells

Supplementary information Supplementary Figures 115 and Supplementary Note 1 (PDF 7798 kb) Supplementary Table 1 (download XLSX Summary of the evaluated DNA methylation assays (XLSX 23 kb) Supplementary Table 2 (download XLSX Summary of the reference samples used for benchmarking (XLSX 13 kb) Supplementary Table 3 (download XLSX Summary of the target genomic regions used for benchmarking (XLSX 316 kb) Supplementary Data 1 (download ZIP Assay documentations provided by the contributing laboratories (ZIP 102924 kb) Supplementary Data 2 (download ZIP Information materials sent to the contributing laboratories (ZIP 953 kb) Supplementary Data 3 (download ZIP Raw data submitted by the contributing laboratories (ZIP 709 kb) Rights and permissions This article is distributed under the terms of the Creative Commons Attribution 4.0 International license ( which permits distribution, and reproduction in any medium, provided the original author and source are credited

Natural Nrf2 activators in diabetes