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doi: 10.1111/nep.12618 170 Sancar-BasSGezginci-OktayogluSBolkentS

Available from: [2] Patricia JJ, Dhamoon AS

Thus, it impairs Ca 2+ efflux through L-type calcium channels, resulting in a reduction in efflux Ca 2+ and an increase in intracellular Ca 2+ , which affects the systolic and diastolic functions of cardiac myocytes (44)

Akter R, Rahman H, Behl T, Chowdhury M, Rahman A, Manirujjaman M, Bungau S (2021) Prospective role of polyphenolic compounds in the treatment of neurodegenerative diseases

High levels of NO, in conjunction with ROS, can lead to the formation of peroxynitrite, a potent oxidant that can induce lipid peroxidation, DNA damage, and protein modification 56