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Parenteral administration of minute amounts of endotoxins to humans elicits an inflammatory reaction typical of SIRS (fever or hypothermia, tachycardia, hyperpnea, leukocytosis, and hypotension), whereas larger amounts of administered endotoxins typically produce sepsis and shock [66, 67]

This blocks DNA synthesis, repair, and cellular replication, primarily targeting rapidly dividing cells, such as cancerous, psoriatic, and immune cells

Microchim Acta 175:355359 Cao M, Cao C, Liu MG, Wang P, Zhu CQ (2009) Selective fluorometry of cytochrome c using glutathione-capped CdTe quantum dots in weakly basic medium

Moreover, amino acid metabolism regulates the redox balance through the generation of nicotinamide adenine dinucleotide phosphate (NADPH) and reduced glutathione (GSH), which are essential for cellular defense against oxidative stressa key driver in IPF progression [7, 19]