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1 Irrespective of the specific urate-lowering therapy (ULT) selected, fundamental principles entail commencing treatment concurrently with prophylaxis and initiating with a conservative dosage, followed by systematic monitoring of serum uric acid levels and subsequent dose adjustment until the therapeutic target is attained

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doi: 10.1038/s41390-022-02415-y Pubmed Abstract CrossRef Google Scholar View reference in article 60 PantellMSilveiraPMendoncaEWingHBrownEKeetonVet al