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Enrofloxacin Possible Side Effects in Dogs and Cats Baytril and enrofloxacin may cause gastrointestinal side effects, including: Vomiting Diarrhea Lack of appetite Abdominal pain Rarely, the following severe side effects may occur: Wobbliness, loss of balance Liver irritation and elevated liver levels Depression Lethargy Seizures Nervousness Aggression Vocalization When used at higher doses in cats, this medication can negatively affect the eyes, causing dilated (larger) pupils, retinal degeneration, or blindness