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Moreover, MAGEL2 expression is disrupted in mice carrying mutations in the core circadian regulator CLOCK ( MAGEL2 is the only gene among those disrupted in Prader-Willi syndrome with expression and function linked to excessive daytime sleepiness and night waking, and while it is also mutated in Schaaf-Yang syndrome, circadian features in this disorder remain poorly characterized due to the small number of diagnosed individuals (Schaaf et al., 2013)

Life 11:62

[DOI] [PubMed] [Google Scholar] [87].Yang IY, Chan G, Miller H, Huang Y, et al

Update 27 (1), 2747

It acts as the literal glue holding your tissues, skin, and joints together