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There are more nerves in the muscle in the thigh than in the deltoid muscle, and it is easier to find the safe place to do the injection in the upper arm (which is why this is a common used place to give vaccinations i.m.)

After the shot, gently move your arm around

Eating a nutritious diet or taking a supplement can help ensure youre meeting your needs however deficiency is common, especially in people who follow a vegetarian or vegan diet as B12 is naturally found in animal foods i.e

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Isoniazid, penicillamine, and some seizure drugs (like phenytoin) may lower vitamin B6 levels, so your provider may adjust doses