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Practical significance is uncertain

The phosphorylated Smad2/3 then connects and moves to Smad4, thereby triggering the transcription of genes responsive to TGF-

We are grateful to Dr Slava Ziegler for discussions of biological experiments

Compounds such as resveratrol (found in grapes) and curcumin (found in turmeric) have demonstrated the ability to activate HATs, promoting histone acetylation and thereby influencing gene transcription (Qi et al